VKORC1 Antibody

Product no.: VKORC1-101AP

$285.00

Description

General Information
Product	VKORC1 Antibody
Description	Vitamin K epoxide reductase complex subunit 1 Antibody
Verified Applications	ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein.
Accession #	GenBank: AJE63371.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.65-0.70 µg/µl in antibody stabilization buffer
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:250
DB	1:50,000
ELISA	1:50,000
Immunocytochemistry	1:250
Immunofluorescence	1:250
Immunohistochemistry	1:250
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q6TEK4
Overview	Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.
Molecular Function	Oxidoreductase, Quinone binding, vitamin-K-epoxide reductase
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein
Expression	Highly expressed in liver. Detected at lower levels in lung, kidney and testis.
Alternative Nomenclature	3-epoxide reductase subunit 1 antibody EDTP308 antibody FLJ00289 antibody IMAGE3455200 antibody MGC2694 antibody MST134 antibody MST576 antibody Phylloquinone epoxide reductase antibody Vitamin K dependent clotting factors deficiency 2 antibody Vitamin K epoxide reductase complex subunit 1 antibody Vitamin K1 2 antibody Vitamin K1 epoxide reductase (warfarin sensitive) antibody VKCFD2 antibody VKOR antibody VKORC1 antibody

Protein information supplied by UniProt