General Information

Product

POP4 Antibody Affinity Purified

Description

Affinity Purified Ribonuclease P protein subunit p29 Antibody C-epitope

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Cat, Human, Monkey, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 170-220 on human Ribonuclease P protein subunit p29 protein.

Accession #

NCBI:  NP_006618.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

O95707

Overview

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P.

Molecular Function

Ribonuclease P activity; RNA binding; tRNA processing

Subcellular Location

Nucleus; Nucleolus

Structure

Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protei

Alternative Nomenclature

EC 3.1.26.5 antibody

hPOP4 antibody

processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) antibody

Ribonuclease P protein subunit p29 antibody

RPP29 antibody

General Information

Product

POP4 Antibody Affinity Purified

Description

Affinity Purified Ribonuclease P protein subunit p29 Antibody N-epitope

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Cat, Human, Monkey, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 140-190 on human Ribonuclease P protein subunit p29 protein.

Accession #

NCBI:  NP_006618.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

O95707

Overview

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P.

Molecular Function

Ribonuclease P activity; RNA binding; tRNA processing

Subcellular Location

Nucleus; Nucleolus

Structure

Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protei

Alternative Nomenclature

EC 3.1.26.5 antibody

hPOP4 antibody

processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) antibody

Ribonuclease P protein subunit p29 antibody

RPP29 antibody

General Information

Product

DDX6 Antibody Affinity Purified

Description

Affinity Purified Probable ATP-dependent RNA helicase DDX6 Antibody

Verified Applications

DB, ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 433-483 on probable ATP-dependent RNA helicase DDX6 protein.

Accession #

NCBI:  NP_004388.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P26196

Overview

In the process of mRNA degradation, may play a role in mRNA decapping.

Molecular Function

ATP-binding, Nucleotide-binding, RNA-binding

Subcellular Location

Cytoplasm; P-body

Expression

Abundantly expressed in most tissues.

Structure

Forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS. Interacts with LIMD1, WTIP and AJUBA. Interacts with APOBEC3G in an RNA-dependent manner. Interacts with RC3H1 (By similarity).

Alternative Nomenclature

ATP dependent RNA helicase DDX6 antibody

ATP dependent RNA helicase p54 antibody

DDX6 antibody

DEAD (Asp Glu Ala Asp) box polypeptide 6 antibody

DEAD box 6 antibody

DEAD box protein 6 antibody

DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase 54kD) antibody

FLJ36338 antibody

HLR2 antibody

Oncogene RCK antibody

P54 antibody

Probable ATP-dependent RNA helicase DDX6 antibody

RCK antibody

General Information

Product

Adiponectin Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Pig

Immunogen

Synthetic peptide taken within amino acid region 150-243 on pig Adiponectin protein.

Accession #

GenBank: AY589691

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.65 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q69907

Overview

Involved in brown fat cell differentiation, responses to drugs, detection of oxidative stress glucose homeostasis and fatty acid oxidation.  Invovled in regulation of DNA biosynthetic processes.

Molecular Function

Hormone activity; receptor binding

Subcellular Location

Cell periphery; collagen trimer; extracellular space; cell surface; endoplasmic reticulum; perinuclear region of cytoplasm

Expression

Secreted

Alternative Nomenclature

30 kDa adipocyte complement related protein antibody

ACDC antibody

ACRP 30 antibody

Adipocyte antibody

Adipocyte C1q and collagen domain containing protein antibody

Adipocyte complement related 30 kDa protein antibody

adipocyte-specific secretory protein antibody

Adiponectin antibody

adiponectin, C1Q and collagen domain containing antibody

AdipoQ antibody

Adipose most abundant gene transcript 1 antibody

Adipose specific collagen like factor antibody

ADIPQTL1 antibody

ADPN antibody

APM 1 antibody

C1q and collagen domain-containing protein antibody

GBP 28 antibody

Gelatin binding protein antibody

Gelatin binding protein 28 antibody

General Information

Product

IBP160 Antibody

Description

Affinity Purified Aquarius Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1250-1300 on human RNA helicase aquarius protein.

Accession #

NCBI:  NP_055506

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.57-0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O60306

Overview

Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP biogenesis

Molecular Function

RNA-binding

Subcellular Location

Nucleus, Spliceosome

Structure

Spliceosome C complex. Component of XAB2 complex.

Alternative Nomenclature

AQR antibody

fSAP164 antibody

functional spliceosome-associated protein 164 antibody

Intron-binding protein of 160 kDa antibody

General Information

Product

NT5C2 Antibody

Description

Affinity Purified 5'-nucleotidase, cytosolic II Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique aino acid sequence on human cNII protein.

Accession #

GenBank: CAI40080

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P49902

Overview

May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.

Molecular Function

Magnesium, Metal-binding, Nucleotide-binding

Subcellular Location

Cytoplasm

Structure

Homotetramer

Alternative Nomenclature

5' nucleotidase (purine) cytosolic type B antibody

cN II antibody

Cytosolic 5''-nucleotidase II antibody

Cytosolic purine 5''-nucleotidase antibody

GMP antibody

NT5B antibody

nt5c2 antibody

NT5CP antibody

NUCLEOTIDASE, 5-PRIME, CYTOSOLIC II antibody

PNT5 antibody

PURINE 5-PRIME-NUCLEOTIDASE antibody

General Information

Product

EHD2 Antibody

Description

Affinity Purified EH domain-containing protein 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse Rat

Immunogen

Synthetic peptide taken within amino acid 420-450 on human EH-Domain Containing Protein 2.

Accession #

NCBI:  NP_055416.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NZN4

Overview

Plays a role in membrane reorganization in response to nucleotide hydrolysis

Molecular Function

ATP binding; GTPase activity; nucleic acid binding; calcium ion binding; GTP binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.

Structure

Homodimer and homooligomer. Interacts with EHD1 and MYOF. May also interact with EHD3 and EHD4.

Alternative Nomenclature

EH domain containing 2 antibody

EH domain containing 3 antibody

EHD 2 antibody

EHD3 antibody

FLJ96617 antibody

PAST 2 antibody

General Information

Product

GCN2 Antibody

Description

Affinity Purified eIF2alpha kinase Antibody

Verified Applications

CM, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1600-1700 on human GCN2 protein.

Accession #

GenBank:  CAB58363.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9P2K8

Overview

Can phosphorylate alpha subunit of EIF2 and mediates translational control.

Molecular Function

ATP binding; Nucleotide binding

Subcellular Location

Cytosolic ribosome

Expression

Liver, brain.

Structure

Contains 2 protein kinase domains; Contains 1 RWD domain.

Alternative Nomenclature

Eif2ak4 antibody

Eukaryotic Translation Initiation Factor 2 alpha kinase 4 antibody

GCN2 antibody

GCN2 eIF2alpha kinase antibody

GCN2 like protein antibody

KIAA1338 antibody

MGCN2 antibody

General Information

Product

Lin28 Antibody

Description

Affinity Purified LIN28 protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid sequence 1-60 on Lin28A sequence.

Accession #

GenBank: AAH28566.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.88-0.95 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q9H9Z2

Overview

Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Association with translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing mRNA's

Molecular Function

DNA binding, mRNA binding, zinc ion binding, miRNA binding, RNA binding

Subcellular Location

Cytoplasm, nucleus, nucleolus. (Note: nucleolar localization observed in 10-15% of nuclei in differentiated byotubes. Shuttles between cytoplasm and nucleus. Localizes to cytoplasmic processing bodies and stress granules)

Expression

Expressed in embryonic stem cells (ES cells), placenta and testis.

Alternative Nomenclature

AL024421 antibody

CSDD1 antibody

FLJ12457 antibody

Lin 28 antibody

Protein lin-28 homolog A antibody

RNA binding protein lin 28 antibody

Tex17 antibody

ZCCHC1 antibody

Zinc finger CCHC domain containing 1 antibody

General Information

Product

nmt55 / NONO / p54nrb Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 430-471 on human NonO protein.

Accession #

GenBank: CAG33042.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q15233

Overview

DNA- and RNA binding protein, involved in several nuclear processes

Molecular Function

Activator, Repressor

Subcellular Location

Nucleus

Expression

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Also found in a number of breast tumor cell lines.

Structure

Monomer and component of the SFPQ-NONO complex

Alternative Nomenclature

52 kDa subunit antibody

54 kDa nuclear RNA and DNA binding protein antibody

DNA-binding p52/p100 complex antibody

NMT 55 antibody

Non Pou domain containing octamer (ATGCAAAT) binding protein antibody

Nono antibody

NRB 54 antibody

P54 antibody

p54nrb antibody