SLC26A3 Antibody

General Information

Product

SLC26A3 Antibody

Description

Affinity Purified Chloride anion exchanger Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids within region 650-700 on human SCL26A3 protein.

Physical Properties

Quantity

100 ug

Concentration

0.5-1.5 ﾵg/ﾵl in antibody stabilization buffer

Immunoglobulin

IgG

Conjugate

Unconjugated

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20ﾡC for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:100

Immunofluorescence

1:50-1:100

Immunohistochemistry

1:50-1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P40879

Overview

Chloride/bicarbonate exchanger. Mediates the efficient absorption of chloride ions in the colon, participating in fluid homeostasis. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.

Subcellular Location

Plasma membrane

Expression

Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon.

Structure

Transmembrane, Transmembrane helix

Alternative Nomenclature

Solute Carrier Family 26 Member 3

DRA

Solute Carrier Family 26 (Anion Exchanger), Member 3

Chloride Anion Exchanger

CLD

Solute Carrier Family 26, Member 3

Down-Regulated In Adenoma Protein

Congenital Chloride Diarrhea

Down-Regulated In Adenoma

Protein DRA