General Information

Product

Calcium Sensing Receptor Antibody

Description

Affinity Purified extracellular calcium-sensing receptor Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Predicted: Rabbit, Horse, Chicken, Cow, Dog, Chimpanzee, Macaque Monkey

Immunogen

Synthetic peptide corresponding to amino acids 47-69 on human CASR gene.

Sequence:

KDQDLKSRPESVECIRYNFRGFR

Accession #

NCBI: NP_000379.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500. Predicted molecular weight: 121 kDa

Protein

Uniprot #

P41180

Overview

Senses change in extracellular concentration of calcium channels.

Molecular Function

GPCR, Receptor, Transducer.

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

Temporal lobe, frontal lobe, parietal lobe, hippocampus, cerebellum, kidney, lung, liver, heart, skeletal muscle and placenta.

Structure

Interacts with VCP, RNF19A and ARRB1.

Alternative Nomenclature

CAR antibody

EIG8 antibody

FHH antibody

FIH antibody

GPRC2A antibody

HHC1 antibody

Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody

NSHPT antibody

Parathyroid Cell calcium-sensing receptor antibody

PCAR1 antibody

General Information

Product

SHISA9 Antibody

Description

Affinity Purified Cytosine-knot AMPA receptor modulating protein 44a Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse

Immunogen

Synthetic peptide taken within amino acid region 250-300 on CKAMP44a protein.

Accession #

NCBI: ADD64956.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9CZN4

Overview

Regulates short term neuronal synaptic plasticity in dentate gyrus.  Also associates with AMPA receptosr in synaptic spines, promotes AMPA receptor desensitization at excitatory synapses.

Molecular Function

Regulation of short-term neuronal synaptic plasticity

Subcellular Location

Cell projection; Single-pass type I membrane protein; Cell junction; Synapse

Expression

Brain specific, expressed mostly in neurons and most brain structures during embryonic and postnatal development.

Structure

Component of some AMPA receptors complex, and atleast composed of some AMPA receloptr, CACNG2, SHISA9 and also  a low level of DLG4

Alternative Nomenclature

CKAMP44 antibody

shisa family member 9 antibody

General Information

Product

DOC2B Antibody

Description

Affinity Purified Double C2-like domain-containing protein beta Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic Peptide taken within amino acid region 360-412 on DOC2b gene.

Accession #

GenBank:  AAB47747.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P70610

Overview

calcium ion-dependent exocytosis of neurotransmitter;positive regulation of insulin secretion

Molecular Function

calcium-dependent phospholipid binding;transporter activity

Subcellular Location

Cell membrane, Cytoplasm, Membrane

Expression

Expressed in brain; highly enriched in neurons

Alternative Nomenclature

Double C2-like domain-containing protein beta antibody

OTTMUSP00000006522 antibody

RP23 78H4.2 antibody

General Information

Product

GIRK1 Antibody

Description

Affinity Purified G protein-activated inward rectifier potassium channel 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Accession #

NCBI: NP_113798

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.60-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P63251

Overview

Potassium channel controlled by G-proteins.  Inward rectifier potassium channel characterized by greater tendency to allow potassium to flow into cell rather than out.  Plays crucial role in regulating heartbeat.

Molecular Function

Potassium

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Associated with GIRK2, GIRK3, GIRK4 to form a G-protein activated heteromultimer pore-forming unit.

Alternative Nomenclature

G protein activated inward rectifier potassium channel 1 antibody

GIRK-1 antibody

Inward rectifier K(+) channel Kir3.1 antibody

Kcnj3 antibody

KGA antibody

KGB1 antibody

Kir3.1 antibody

Potassium channel antibody

Potassium channel, inwardly rectifying subfamily J member 3 antibody

General Information

Product

GIRK2 Antibody Affinity Purified

Description

Affinity Purified G protein-activated inward rectifier potassium channel 2 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid 1-50 on human GIRK2 protein.

Accession #

GenBank: Q8QZW1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.60-0.61 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8QZW1

Overview

G-protein activated inward rectifier potassium channel activity.

Molecular Function

Potassium

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Belongs to inward rectifier-type potassium channel family

Alternative Nomenclature

BIR1 antibody

G protein-activated inward rectifier potassium channel 2 antibody

hiGIRK2 antibody

Inward rectifier K(+) channel Kir3.2 antibody

Inward rectifier potassium channel KIR3.2 antibody

inwardly rectifying subfamily J member 6 antibody

KATP-2 antibody

Kcnj6 antibody

Kcnj7 antibody

KIR3.2 antibody

Potassium channel antibody

General Information

Product

GIRK3 Antibody Affinity Purified

Description

Affinity Purified G protein-activated inward rectifier potassium channel 3 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid region on human GIRK3 protein.

Accession #

NCBI:  NP_004974.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q92806

Molecular Function

Potassium

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Belongs to inward rectifier-type potassium channel family

Alternative Nomenclature

G protein activated inward rectifier potassium channel 3 antibody

GIRK3 antibody

Inward rectifier K(+) channel Kir3.3 antibody

inwardly rectifying subfamily J member 9 antibody

Kcnj9 antibody

KIR3.3 antibody

Potassium channel antibody

Potassium channel inwardly rectifying subfamily J member 9 antibody

General Information

Product

GIRK4 Antibody Affinity Purified

Description

Affinity Purified G protein-activated inward rectifier potassium channel 4 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 350-450 on human GIRK4 protein.

Accession #

NCBI: NP_000881

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.53-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P48544

Molecular Function

Potassium

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Belongs to inward rectifier-type potassium channel family

Alternative Nomenclature

Cardiac ATP sensitive potassium channel antibody

Cardiac inward rectifier antibody

CIR antibody

G protein activated inward rectifier potassium channel 4 antibody

GIRK-4 antibody

Heart KATP channel antibody

Inward rectifier K+ channel KIR3.4 antibody

IRK-4 antibody

KATP-1 antibody

KCNJ 5 antibody

KIR3.4 antibody

Potassium channel antibody

General Information

Product

GPCR GPR15 Antibody

Description

Affinity Purified G-protein coupled receptor 15 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse

Immunogen

Synthetic peptide taken within amino acid region 320-360 on human GPCR GPR15 protein.

Accession #

NCBI: NP_005281

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P49685

Overview

Chemokine receptor; Alternative correceptor with CD4 for HIV-1 infection.

Molecular Function

GPCR; Receptor; Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Structure

Belongs to G-protein coupled receptor 1 family.

Alternative Nomenclature

BOB antibody

Brother of Bonzo antibody

G protein coupled receptor 15 antibody

G protein coupled receptor GPR15 antibody

General Information

Product

GPR56 Extracellular domain Antibody

Description

Affinity Purified G-protein coupled receptor 56 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse

Predicted: Rat

Immunogen

Synthetic peptide taken from large extracellular loop of the human GPCR56 protein. Peptide was conjugated to Keyhole Limpet Haemocyanin (KLH).

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q9Y653

Overview

Involved in cell adhesion and probably in cell-cell interactions.

Molecular Function

Developmental protein, G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Membrane, Secreted

Expression

highest levels found in thyroid gland, brain and heart;Expressed in a great number of tumor cells.

Structure

Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily

Alternative Nomenclature

7 transmembrane protein with no EGF like N terminal domains 1 antibody

BFPP antibody

DKFZp781L1398 antibody

EGF TM7 like antibody

G protein coupled receptor 56 antibody

Gpr56 antibody

Polymicrogyria bilateral frontoparietal antibody

Protein TM7XN1 antibody

TM7LN4 antibody

TM7XN1 protein antibody

General Information

Product

Norepinephrine Transporter Antibody

Description

Affinity Purified Sodium -dependent noradrenaline transporter Antibody

Verified Applications

Dot Blot, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to N-terminal amino acids that are unique to noradrenaline transporter protein. The antibodies are raised utilizing linear, multiple antigenic peptides or cyclic peptide methodology.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage Instructions

Shipped at 4⁰C. Upon delivery aliquot and store at -20⁰C or -80⁰C. Avoid repeated freeze / thaw cycles.

pH: 7.80
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris glycine, 30% Glycerol

Application Protocol

Confocal Microscopy

1:100

DB

1:4,000

ELISA

1:4,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P23975

Overview

Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.

Molecular Function

monoamine transmembrane transporter activity; norepinephrine:sodium symporter activity

Subcellular Location

Membrane

Expression

Adrenal gland; Placenta; Testis; Skin

Structure

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.

Alternative Nomenclature

NAT1 antibody

NET antibody

NET1 antibody

Neurotransmitter transporter antibody

Norepinephrine transporter antibody

SLC6A2 antibody

SLC6A5 antibody

Sodium dependent noradrenaline transporter antibody

Solute carrier family 6 (neurotransmitter transporter norepinephrine) member 5 antibody

Solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 antibody

Solute carrier family 6 member 2 antibody

Solute carrier family 6 member 5 antibody