General Information

Product

TSH beta Antibody

Description

Affinity Purified Thyroid stimulating hormone, beta Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 human TSH beta chain protein.

Accession #

GenBank: AAH69298.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.63-0.69 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Dot Blot

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

P01222

Overview

Indespensable for the control of thyroid structure and metabolism.

Molecular Function

hormone activity

Subcellular Location

Secreted

Alternative Nomenclature

CHNG4 antibody

Thyroid stimulating hormone beta subunit antibody

Thyrotropin beta subunit antibody

TSHB antibody

General Information

Description

Affinity Purified Estrogen Receptor Antibody Mid Region

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide taken within amino acid region 520-570 on human Estrogen receptor alpha protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid Region

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P03372

Overview

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues

Molecular Function

Activator, Receptor

Subcellular Location

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus

Expression

Widely expressed. Isoform 3 is not expressed in the pituitary gland

Structure

Belongs to the nuclear hormone receptor family. NR3 subfamily

Alternative Nomenclature

DKFZp686N23123 antibody

ER alpha antibody

ER antibody

Era antibody

ESR antibody

ESR1 antibody

ESRA antibody

Estradiol receptor antibody

Estrogen nuclear receptor alpha antibody

Estrogen receptor 1 antibody

Estrogen receptor antibody

ESTRR antibody

Major ORF antibody

NR3A1 antibody

Nuclear receptor subfamily 3 group A member 1 antibody

General Information

Product

Estrogen Receptor alpha Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 545-595 on human Estrogen receptor alpha protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P03372

Overview

Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Molecular Function

Activator, Receptor

Subcellular Location

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus

Expression

Widely expressed. Isoform 3 is not expressed in the pituitary gland

Structure

Belongs to the nuclear hormone receptor family. NR3 subfamily

Alternative Nomenclature

DKFZp686N23123 antibody

ER alpha antibody

ER antibody

Era antibody

ESR antibody

ESR1 antibody

ESRA antibody

Estradiol receptor antibody

Estrogen nuclear receptor alpha antibody

Estrogen receptor 1 antibody

Estrogen receptor antibody

ESTRR antibody

Major ORF antibody

NR3A1 antibody

Nuclear receptor subfamily 3 group A member 1 antibody

General Information

Product

hCG beta Antibody

Description

Affinity Purified Choriogonadotropin subunit beta Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 131-149 on human Chorionic gonaotropin beta protein.

Specificity

This antibody will detect CGB1, CGB2, CGB5, CGB7, CGB8.

Accession #

NCBI:  NP_203695.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

A6NKQ9

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Expressed in placenta, testis and pituitary.

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB 3 antibody

CGB 5 antibody

CGB 7 antibody

CGB antibody

CGB8 antibody

Choriogonadotropin subunit beta antibody

Chorionic gonadotrophin chain beta antibody

Chorionic gonadotropin beta polypeptide antibody

Chorionic gonadotropin beta subunit antibody

hCGB antibody

Human Chorionic Gonadotropin antibody

General Information

Product

hCG beta Antibody

Description

Affinity Purified Choriogonadotropin subunit beta Antibody Extreme C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 142-165 on human Chorionic gonaotropin beta protein.

Specificity

This antibody will detect CGB1, CGB2, CGB5, CGB7, CGB8.

Accession #

NCBI:  NP_203695.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Extreme C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

A6NKQ9

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Expressed in placenta, testis and pituitary.

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB 3 antibody

CGB 5 antibody

CGB 7 antibody

CGB antibody

CGB8 antibody

Choriogonadotropin subunit beta antibody

Chorionic gonadotrophin chain beta antibody

Chorionic gonadotropin beta polypeptide antibody

Chorionic gonadotropin beta subunit antibody

hCGB antibody

Human Chorionic Gonadotropin antibody

General Information

Product

hCG beta 2 Antibody

Description

Affinity Purified Choriogonadotropin subunit beta 2 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human choriogonadotropin subunit beta variant 2 protein.

Specificity

This antibody will detect CGB2 only.

Accession #

GenBank: AAH69367.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

H9KV56

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Placenta

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB antibody

CGB2 antibody

Chorionic gonadotropin beta 2 subunit antibody

Chorionic gonadotropin beta chain antibody

Chorionic gonadotropin beta polypeptide antibody

hCGB2 antibody

Human Chorionic Gonadotropin antibody

General Information

Product

hCG beta 2 Antibody

Description

Affinity Purified Choriogonadotropin subunit beta 2 Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 82-132 on human choriogonadotropin subunit beta variant 2 protein.

Specificity

This antibody will detect CGB2 only.

Accession #

GenBank: AAH69367.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

H9KV56

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Placenta

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB antibody

CGB2 antibody

Chorionic gonadotropin beta 2 subunit antibody

Chorionic gonadotropin beta chain antibody

Chorionic gonadotropin beta polypeptide antibody

hCGB2 antibody

Human Chorionic Gonadotropin antibody

General Information

Product

Legumain Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human Legumain protein.

Accession #

NCBI:  XP_016876954

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q99538

Overview

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

Subcellular Location

Lysosome

Expression

Ubiquitous. Particularly abundant in kidney, heart and placenta.

Structure

In the zymogen form, the uncleaved propeptide blocks access to the active site.

Alternative Nomenclature

AEP antibody
Asparaginyl endopeptidase antibody
cysteine 1 antibody
Cysteine protease 1 antibody
Legumain antibody
LGMN antibody
LGMN1 antibody
Protease antibody
Protease cysteine 1 (legumain) antibody
Protease cysteine 1 antibody
PRSC1 antibody

General Information

Product

Aromatase Antibody

Description

Affinity Purified Aromatase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-450 on human Aromatase protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P11511

Overview

Catalyzes the formation of aromatic C18 estrogens from C19 androgens.

Molecular Function

aromatase activity

electron carrier activity

heme binding

iron ion binding

Subcellular Location

Membrane; Peripheral membrane protein

Expression

Widely expressed, including in adult and fetal brain, placenta, skin fibroblasts, adipose tissue and gonads.

Structure

Belongs to the cytochrome P450 family.

Alternative Nomenclature

ARO antibody

ARO1 antibody

Aromatase antibody

CP19A_HUMAN antibody

CPV1 antibody

CYAR antibody

Cyp19a1 antibody

CYPXIX antibody

Cytochrome P-450AROM antibody

Cytochrome P450, family 19, subfamily A, polypeptide 1 antibody

Cytochrome P450, subfamily XIX (aromatization of androgens) antibody

Estrogen synthase antibody

Flavoprotein linked monooxygenase antibody

Microsomal monooxygena

450AROM antibody