ABHD2 Antibody

Product no.: ABHD2-201AP

$285.00

Description

General Information
Product	ABHD2 Antibody
Description	Affinity Purified a/b hydrolase II Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 200-250 on mouse a/b hydrolase II protein.
Accession #	GenBank: AAQ12022.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Purification Method	Immobilized antigen affinity chromatography
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q9QXM0
Overview	Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Involved in acrosomal reaction (PubMed:26989199). May also play a role in smooth muscle cells migration.
Molecular Function	Hydrolase, Serine esterase
Subcellular Location	Cell membrane; Single-pass type II membrane protein Cytoplasmic vesicle › secretory vesicle › acrosome membrane
Expression	Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.
Structure	Signal-anchor, Transmembrane, Transmembrane helix
Alternative Nomenclature	abhydrolase domain containing 2 antibody alpha/beta hydrolase domain containing protein 2 antibody HS1 2 antibody LABH2 antibody Lung alpha/beta hydrolase 2 antibody PHPS1 2 antibody protein PHPS1-2 antibody

Protein information supplied by UniProt