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General Information
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Product
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ABHD2 Peptide
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Description
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Antigenic Blocking Peptide a/b hydrolase II
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 200-250 on mouse a/b hydrolase II protein.
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Accession #
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GenBank: AAQ12022.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9QXM0
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Overview
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Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Involved in acrosomal reaction (PubMed:26989199). May also play a role in smooth muscle cells migration.
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Molecular Function
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Hydrolase, Serine esterase
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Subcellular Location
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Cell membrane; Single-pass type II membrane protein
Cytoplasmic vesicle › secretory vesicle › acrosome membrane
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Expression
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Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.
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Structure
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Signal-anchor, Transmembrane, Transmembrane helix
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Alternative Nomenclature
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2210009N18Rik antibody
abhydrolase domain containing 2 antibody
alpha/beta hydrolase domain containing protein 2 antibody
HS1 2 antibody
LABH2 antibody
Lung alpha/beta hydrolase 2 antibody
PHPS1 2 antibody
protein PHPS1-2 antibody
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ABHD2 Antibody
ABHD2 Antibody BIOTIN
ABHD2 Antibody FITC
ABHD2 Positive Control
