CCR2 Antibody

General Information

Product

CCR2 Antibody

Description

Affinity Purified C-C chemokine receptor type 2 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 20-70 on human CCR2 protein.

Accession #

NCBI: NP_955783

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.71 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P41597

Overview

Receptor for CCL2, CCL7 and CCL13 chemokines.  Transduces a signal by increasing intracellular calcium ion levels.  Alternative coreceptor with CD4 for HIV-1 infection.

Molecular Function

Host-virus interaction; GPCR; Transducer

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

Induced; Up-regulated by CREB3

Structure

Binds to HIV-1 Tat.  Interacts with ARRB1

Alternative Nomenclature

CC CKR 2 antibody

CD192 antibody

CKR2A antibody

CKR2B antibody

CMKBR2 antibody

MCP1 RECEPTOR antibody

Monocyte chemoattractant protein 1 receptor antibody