CTLA4 Antibody


CTLA4 Antibody

Product no.: CTLA4-101AP
$295.00
$265.00


General Information

 

 

Product

 

CTLA4 Antibody

Description

Affinity Purified Cytotoxic T-lymphocyte protein 4 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 on human CTLA4 protein.

Accession #

GenBank: AAL07473.1


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

ELISA

 

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500


Protein

 

Uniprot #

 

P16410

Overview

Inhibitory receptor acting as a major negative regulator of T-cell responses.  The affinity of CTLA4 for its natural B7 family lingands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory correceptor CD28.

Molecular Function

Adaptive Immunity

Subcellular Location

Cell membrane; Single pass type I membrane protein

Expression

Widely expressed with highest levels in lymphoid tissues.  Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory correceptor, on the cell surface following activation.

Structure

Homodimer; disfulfide-linked

Alternative Nomenclature

CD 152 antibody

CD antibody

CD152 antigen antibody

CD152 isoform antibody

Celiac disease 3 antibody

CELIAC3 antibody

CTLA-4 antibody

Cytotoxic T cell associated 4 antibody

Cytotoxic T lymphocyte associated serine esterase 4 antibody

GRD4 antibody

GSE antibody

ICOS antibody

IDDM12 antibody

Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody

   

Protein information supplied by by UniProt
 

 

Accessories

Product Note Status Price
CTLA4 Antibody FITC CTLA4 Antibody FITC
CTLA4-FITC $350.00 *
CTLA4 Antibody BIOTIN CTLA4 Antibody BIOTIN
CTLA4-BIOTIN $350.00 *
CTLA4 Blocking Peptide CTLA4 Blocking Peptide
P-CTLA4 $145.00 *
CTLA4 Positive Control CTLA4 Positive Control
PC-CTLA4 $185.00 *
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Browse these categories as well: CD, Diagnostic Markers, Autoimmune, Primaries, Lymphoid, T Cells, Cytotoxic Cells