Factor XIIIa Antibody

General Information

Product

FXIIIA Antibody

Description

Affinity Purified Blood coagulation factor XIII a subunit Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Monkey, Mouse

Immunogen

Synthetic peptide taken within amino acid region 700-732 on human factor XIII A subunit protein.

Accession #

GenBank: AAA52415.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P00488

Overview

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Molecular Function

Metal ion binding; Protein-glutamine gamma-glutamyltransferase activity

Subcellular Location

Cytoplasm. Secreted

Structure

Tetramer of two A chains and two B chains.

Alternative Nomenclature

bA525O21.1 (coagulation factor XIII, A1 polypeptide) antibody

Coagulation factor XIII A chain antibody

F13A antibody

F13A1 antibody

Fibrin stabilizing factor, A subunit antibody

Fibrinoligase antibody

FSF, A subunit antibody

FXIIIA antibody

Protein-glutamine gamma-glutamyltransferase A chain antibody

TGase antibody

Transglutaminase A chain antibody