Histone H3 Antibody

Product no.: HH3-312AP
$285.00


General Information

 

 

Product

 

Histone H3 Antibody

Description

Affinity Purified Histone H3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, S. cerevisiae

Immunogen

Synthetic peptide taken within amino acid 1-50 on Sacchoromyces cerevisiae protein HH3 protein.

Accession #

Gen Bank: EDZ69636.1


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunohistochemistry 1:100

Immunoprecipitation

1:150

Western Blot

1:500


Protein

 

Uniprot #

 

B5VR08

Overview

Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Can bind to DNA (in vitro).

Molecular Function

Chromatin regulator, Methyltransferase, Transferase

Subcellular Location

Nucleus

Structure

Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.

Contains 1 DOT1 domain.

Alternative Nomenclature

H3 histone family, member J antibody

H3 histone antibody

H3 histone family, member A antibody

H3 histone family, member B antibody

H3 histone family, member C antibody

H3 histone family, member D antibody

H3 histone family, member F antibody

H3 histone family, member H antibody

H3 histone family, member I antibody

H3 histone family, member K antibody

H3 histone family, member L antibody

H3 histone, family 3A antibody

H3.3A antibody

H3F1K antibody

H3F3 antibody

Histone cluster 1, H3a antibody

Histone cluster 1, H3b antibody

Histone cluster 1, H3c antibody

Histone cluster 1, H3d antibody

Histone cluster 1, H3e antibody

Histone cluster 1, H3f antibody

Histone cluster 1, H3g antibody

Histone cluster 1, H3i antibody

Histone cluster 1, H3j antibody

   

Protein information supplied by UniProt

Accessories

Product Note Status Price
Histone H3 Antibody FITC Histone H3 Antibody FITC
HH3.312-FITC $375.00 *
Histone H3 Antibody BIOTIN Histone H3 Antibody BIOTIN
HH3.312-BIOTIN $375.00 *
Histone H3 Blocking Peptide Histone H3 Blocking Peptide
P-HH3.312 $155.00 *
Histone H3 Positive Control Histone H3 Positive Control
PC-HH3 $200.00 *
Display accessory details

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HH3-301AP
PHH3-340AP

Browse these categories as well: Histones, Diagnostic Markers, ChIP, Transcription, Regulation, DNA Damage Response, Primaries