Indoleamine 2 3-dioxygenase 2 Antibody

Product no.: IDO2-201AP

$285.00

Description

General Information
Product	Indoleamine 2, 3-dioxygenase 2 Antibody
Description	Affinity Purified Indoleamine 2,3-dioxygenase 1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey
Immunogen	Synthetic peptide taken within amino acid region 370-420 on human Indoleamine 2,3-dioxygenase 2 protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5-1.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Purification Method	Immobilized antigen affinity chromatography
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:50,000
Immunohistochemistry	1:50-1:250
Immunoprecipitation	1:200
Western Blot	1:2,500-1:5,000
Protein
Uniprot #	Q6ZQW0
Overview	Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance.
Molecular Function	heme binding indoleamine 2,3-dioxygenase activity metal ion binding tryptophan 2,3-dioxygenase activity
Subcellular Location	cytosol
Expression	Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%).
Structure	Belongs to the indoleamine 2,3-dioxygenase family.
Alternative Nomenclature	3-dioxygenase antibody I23O1_HUMAN antibody IDO 2 antibody IDO antibody IDO-2 antibody IDO2 antibody INDO antibody indolamine 2,3 dioxygenase antibody Indole 2 3 dioxygenase antibody indoleamine 2 3 dioxygenase 1 antibody indoleamine 2 3 dioxygenase antibody Indoleamine 2,3-dioxygenase 1 antibody Indoleamine pyrrole 2 3 dioxygenase antibody Indoleamine-pyrrole 2 antibody

Protein information supplied by UniProt.