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General Information
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Product
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Indoleamine 2, 3-dioxygenase 2 Peptide
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Description
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Antigenic Blocking Peptide Indoleamine 2,3-dioxygenase 2 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 370-420 on human Indoleamine 2,3-dioxygenase 2 protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q6ZQW0
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Overview
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Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance.
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Molecular Function
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heme binding
indoleamine 2,3-dioxygenase activity
metal ion binding
tryptophan 2,3-dioxygenase activity
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Subcellular Location
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cytosol
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Expression
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Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%).
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Structure
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Belongs to the indoleamine 2,3-dioxygenase family.
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Alternative Nomenclature
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3-dioxygenase antibody
I23O1_HUMAN antibody
IDO 2 antibody
IDO antibody
IDO-2 antibody
IDO2 antibody
INDO antibody
indolamine 2,3 dioxygenase antibody
Indole 2 3 dioxygenase antibody
indoleamine 2 3 dioxygenase 1 antibody
indoleamine 2 3 dioxygenase antibody
Indoleamine 2,3-dioxygenase 1 antibody
Indoleamine pyrrole 2 3 dioxygenase antibody
Indoleamine-pyrrole 2 antibody
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Indoleamine 2 3-dioxygenase 2 Antibody FITC
Indoleamine 2 3-dioxygenase 2 Antibody
Indoleamine 2 3-dioxygenase 2 Antibody BIOTIN
Indoleamine 2 3-dioxygenase 2 Positive Control
