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General Information
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Product
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Aph 1b Peptide
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Description
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Antigenic Blocking Peptide Presenelin-stabiliziation factor-like Antibody
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Verified Applications
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Immmunodepletion, Competition Assay
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Peptide Description
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Synthetic peptide taken within amino acid region 235-257 of Human Presenilin stabilizing protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q8WW43
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Overview
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Subunit of gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and beta-amyloid precursor protein.
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Molecular Function
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Notch signaling pathway
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Subcellular Location
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Membrane; Multi-pass protein
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Expression
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Weakly expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle, heart, and brain.
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Structure
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Component of gamma-secretase complex. Interacts with PSEN1 and PSEN2.
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Alternative Nomenclature
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Anterior pharynx defective 1B like antibody
Gamma secretase subunit APH 1B antibody
Presenilin stabilisation factor like antibody
PRO1328 antibody
PSFL antibody
TAAV 688 antibody
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Aph 1b Antibody
Aph 1b Antibody FITC
Aph 1b Antibody BIOTIN
Aph 1b Positive Control
