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General Information
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Product
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Axl Peptide
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Description
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Antigenic Blocking Peptide AXL receptor tyrosine kinase UFO isoform 1
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Verified Applications
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Immmunodepletion, Competition Assay
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Peptide Description
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Synthetic peptide taken within amino acid region 840-880 on mouse AXL protein. The peptide was post translationally modified to acheive proper orientation and antigenicity.
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Accession #
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NCBI: NP_033491
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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1:500
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Protein
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Uniprot #
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Q00993
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Overview
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Receptor tyrosine kinase that transduces signals from the ECM into cytoplasm by binding growth factor GAS6. Regulates survival, proliferation, migration and differentiation.
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Molecular Function
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ATP-binding, Nucleotide binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase, Immunity Differentation and Innate Immunity
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Subcellular Location
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Cell membrane; Single-pass type II membrane protein
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Expression
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Developing tissues in late embryogenesis. In cells forming organ capsules as well as in connective tissue structures in adult.
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Structure
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Heterodimer and heterotetramer with ligand GAS6.
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Alternative Nomenclature
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Adhesion related kinase antibody
Ark antibody
Tyro7 antibody
Tyrosine protein kinase receptor UFO antibody
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Axl Antibody
Axl Antibody FITC
Axl Antibody BIOTIN
Axl Positive Control
