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General Information
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Product
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MeCP2 isoform 1 Peptide
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Description
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Antigenic Blocking Peptide Methyl-CpG-binding Protein 2 isoform 1
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| Species |
Human, Mouse |
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 1-50 on mouse Methyl-CpG-binding Protein 2 isoform 1 protein.
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Accession #
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NCBI: XP_006538787
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9Z2D6
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Overview
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Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
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Molecular Function
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chromatin binding
DNA binding
DNA binding transcription factor activity
double-stranded methylated DNA binding
methyl-CpG binding
mRNA binding
protein domain specific binding
protein N-terminus binding
siRNA binding
transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
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Subcellular Location
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Nucleus
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Alternative Nomenclature
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AUTSX3 antibody
Mbd5 antibody
MECP 2 antibody
MeCP 2 protein antibody
MeCP2 antibody
Methyl CpG binding protein 2 (Rett syndrome) antibody
Methyl CpG binding protein 2 antibody
MRX 16 antibody
MRX 79 antibody
MRXS13 antibody
MRXSL antibody
PPMX antibody
RS antibody
RTS antibody
RTT antibody
WBP10 antibody
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MeCP2 isoform 1 Antibody
MeCP2 isoform 1 Antibody BIOTIN
MeCP2 isoform 1 Antibody FITC
MeCP2 isoform 1 Positive Control
