PDE4C Blocking Peptide

FabGennix PDE4C Antibody has been used in 15 Publications

Applications: Coimmunoprecipitation, Immunocytochemistry, Immunohistochemistry, and Western blot

Reactivity: Human, Mouse, and Rat

Cheng, Hao, et al. "siRNA‑mediated silencing of phosphodiesterase 4B expression affects the production of cytokines in endotoxin‑stimulated primary cultured microglia." Experimental and Therapeutic Medicine 12.4 (2016).

PMID: 27698721

Applications: Western Blot

Reactivity: Rat

Ji, Qing, et al. "Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation." Molecular medicine reports 13.2 (2016).

PMCID: 26706904

Applications: Western Blot

Reactivity: Rat

Massimi, Mara, et al. "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." Journal of Cellular Biochemistry (2016).

PMCID: 27859531

Applications: Western Blot

Reactivity: Human

Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015).

PMID: 25578602

Applications: Immunohistochemistry

Reactivity: Human

Yougbaré, Issaka, et al. "NCS 613 Exhibits Anti-Inflammatory Effects On Pbmcs From Lupus Patients By Inhibiting P38 MAPK And NF-Κb Signalling Pathways While Reducing Proinflammatory Cytokine Production." Canadian Journal Of Physiology & Pharmacology 91.5 (2013).

PMID: 23656347

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Haque, Mohammed Z., Paulo S. Caceres, and Pablo A. Ortiz. “β-Adrenergic Receptor Stimulation Increases Surface NKCC2 Expression in Rat Thick Ascending Limbs in a Process Inhibited by Phosphodiesterase 4.” American Journal of Physiology - Renal Physiology 303.9 (2012).

PMCID: 3518189

Applications: Western Blot

Reactivity: Rat

Keravis, Thérèse et al. “Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor.” Ed. Pierre Bobé. PLoS ONE 7.1 (2012).

PMCID: 3256138

Applications: Western Blot

Reactivity: Mouse

Abusnina, Abdurazzag, et al. "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." Cellular signalling 23.1 (2011).

PMID: 20807569

Applications: Western Blot

Reactivity: Human

Yougbare, Issaka, et al. "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on Human lung tissues." American Journal of Physiology-Lung Cellular and Molecular Physiology 301.4 (2011).

PMID: 21784969

Applications: Immunocytochemistry, Western Blot

Reactivity: Human

Tahseldar-Roumieh, Rima et al. “PDEs1-5 Activity and Expression in Tissues of Cirrhotic Rats Reveal a Role for Aortic PDE3 in NO Desensitization.” International Journal of Experimental Pathology 90.6 (2009).

PMID: 2803251

Applications: Western Blot

Reactivity: Rat

Whitaker, Christopher M., and Nigel G. F. Cooper. “The Novel Distribution of Phosphodiesterase-4 Subtypes Within the Rat Retina.” Neuroscience 163.4 (2009).

PMCID: 2774823

Applications: Western Blot

Reactivity: Rat

Campos-Toimil, M et al. “Short-Term or Long-Term Treatments with a Phosphodiesterase-4 (PDE4) Inhibitor Result in Opposing Agonist-Induced Ca2+ Responses in Endothelial Cells.” British Journal of Pharmacology 154.1 (2008).

PMCID: 2438981

Applications: Western Blot

Reactivity: Human

Sachs, Benjamin D. et al. “P75 Neurotrophin Receptor Regulates Tissue Fibrosis through Inhibition of Plasminogen Activation via a PDE4/cAMP/PKA Pathway.” The Journal of Cell Biology 177.6 (2007).

PMCID: 2064370

Applications: Coimmunoprecipitation,

Western Blot

Reactivity: Mouse

Murray, Fiona, et al. "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." American Journal of Physiology-Lung Cellular and Molecular Physiology 292.1 (2007).

PMID: 16980375

Applications: Western Blot

Reactivity: Human

Gallagher, Helen C., et al. "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." Neurotoxicology and teratology 26.1 (2004).

PMID: 15001216

Applications: Western Blot

Reactivity: Human