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General Information
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Product
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PDE7A Peptide
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Description
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Antigenic Blocking Peptide cAMP-specific cyclic nucleotide phosphodiesterase PDE7A3
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic cyclic peptide common to all PDE7A variants
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Accession #
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GenBank: AAK57640.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q13946
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.
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Molecular Function
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3', 5' -cyclic-AMP phosphodiesterase activity
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Subcellular Location
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Isoform PDE7A1 : Cytoplasm › cytosol, Isoform PDE7A2: Cytoplasm
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Expression
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PDE7A1 is found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. PDE7A2 is found abundantly in skeletal muscle and at low levels in heart.
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Structure
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Interacts with CBFA2T3
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Alternative Nomenclature
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HCP 1 antibody
P2A antibody
PDE 7 antibody
PDE1/PDE2 yeast human complement of antibody
PDE7A antibody
Phosphodiesterase 7A antibody
Phosphodiesterase isozyme 7 antibody
Rolipram insensitive phosphodiesterase type 7 antibody
TM 22 antibody
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PDE7A Antibody
PDE7A Antibody FITC
PDE7A Antibody BIOTIN
PDE7A Positive Control
