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General Information
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Product
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PD-L2 Peptide
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Description
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Antigenic Blocking Peptide Programmed cell death 1 ligand 2 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 115-165 on human Programmed cell death 1 ligand 2 protein.
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Accession #
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NCBI: NP_079515
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9BQ51
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Overview
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Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
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Molecular Function
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Receptor
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Subcellular Location
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Isoform 3 : Secreted
Isoform 2 : Endomembrane system, Single-pass type I membrane protein
Isoform 1 : Cell membrane, Single-pass type I membrane protein
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Expression
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Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
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Structure
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Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
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Alternative Nomenclature
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B7 dendritic cell molecule antibody
B7-DC antibody
bA574F11.2 antibody
Btdc antibody
Butyrophilin B7 DC antibody
CD 273 antibody
PD 1 ligand 2 antibody
PD-L2 antibody
PDCD 1 ligand 2 antibody
PDCD1L2 antibody
Pdcd1lg2 antibody
Programmed cell death 1 ligand 2 antibody
Programmed death ligand 2 antibody
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PD-L2 Antibody
PD-L2 Antibody BIOTIN
PD-L2 Antibody FITC
PD-L2 Positive Control
