PD-L2 Antibody

Product no.: PDL2-201AP

$285.00

Description

General Information
Product	PD-L2 Antibody
Description	Affinity Purified Programmed cell death 1 ligand 2 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey Predicted: Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 115-165 on human Programmed cell death 1 ligand 2 protein.
Accession #	NCBI: NP_079515
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Purification Method	Immobilized antigen affinity chromatography
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q9BQ51
Overview	Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Molecular Function	Receptor
Subcellular Location	Isoform 3 : Secreted Isoform 2 : Endomembrane system, Single-pass type I membrane protein Isoform 1 : Cell membrane, Single-pass type I membrane protein
Expression	Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Structure	Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Alternative Nomenclature	B7 dendritic cell molecule antibody B7-DC antibody Btdc antibody Butyrophilin B7 DC antibody CD 273 antibody PD 1 ligand 2 antibody PD-L2 antibody PDCD 1 ligand 2 antibody PDCD1L2 antibody Pdcd1lg2 antibody Programmed cell death 1 ligand 2 antibody Programmed death ligand 2 antibody

Protein information supplied by UniProt