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General Information
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Product
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PTIP Peptide
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Description
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Antigenic Blocking Peptide PAX-interacting protein 1 Antibody
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Verified Applications
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Immunocompetition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 1000-1069 on human PTIP protein.
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Accession #
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NCBI: NP_031375
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q6ZW49
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Overview
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Involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. Plays a role in early development. In DNA damage response is required for cell survival after ionizing radiation. In vitro shown to be involved in the homologous recombination mechanism for the repair of double-strand breaks (DSBs).
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Subcellular Location
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Nucleus matrix
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Structure
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Interacts with the C-terminal transactivation domain of PAX2 (By similarity). Interacts with PAGR1; the interaction is direct and also occurs independent of MLL-containing complexes. Interacts with TP53BP1 (phosphorylated at 'Ser-25'). Interacts with HLTF
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Alternative Nomenclature
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CAGF 28 antibody
CAGF 29 antibody
PACIP1 antibody
PAX-interacting protein 1 antibody
Protein encoded by CAG trinucleotide repeats antibody
PTIP antibody
TNRC2 antibody
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PTIP Antibody
PTIP Antibody FITC
PTIP Antibody BIOTIN
PTIP Positive Control
