General Information
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Product
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PTIP Positive Control
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Description
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Western Blot Positive Control PAX-interacting protein 1
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Verified Applications
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WB
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Concentration |
The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel. |
Storage
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-20⁰C for long term storage
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Protein
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Uniprot #
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Q6ZW49
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Overview
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Involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. Plays a role in early development. In DNA damage response is required for cell survival after ionizing radiation. In vitro shown to be involved in the homologous recombination mechanism for the repair of double-strand breaks (DSBs).
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Subcellular Location
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Nucleus matrix
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Structure
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Interacts with the C-terminal transactivation domain of PAX2 (By similarity). Interacts with PAGR1; the interaction is direct and also occurs independent of MLL-containing complexes. Interacts with TP53BP1 (phosphorylated at 'Ser-25'). Interacts with HLTF
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Alternative Nomenclature
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CAGF 28 antibody
CAGF 29 antibody
PACIP1 antibody
PAX-interacting protein 1 antibody
Protein encoded by CAG trinucleotide repeats antibody
PTIP antibody
TNRC2 antibody
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