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General Information
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Product
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SFRP5 Peptide
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Description
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Antigenic Blocking Peptide Secreted frizzled-related protein 5 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 150-200 on SFRP5 protein.
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Accession #
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GenBank: AAD25052.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q5T4F7
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Overview
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Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
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Molecular Function
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PDZ domain binding, Wnt-protein binding, Wnt-activated receptor activity
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Subcellular Location
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Secreted
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Expression
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Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle.
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Alternative Nomenclature
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Frizzled related protein 1b
FRP 1b
SARP3
Secreted apoptosis related protein 3
Secreted frizzled related protein 5
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SFRP5 Antibody
SFRP5 Antibody FITC
SFRP5 Antibody BIOTIN
SFRP5 Positive Control
