SFRP5 Positive Control

General Information

Product

SFRP5 Western Blot Positive Control

Description

Western Blot Positive Control Secreted frizzled-related protein 5 

Verified Applications

WB

Accession #

GenBank: AAD25052.1

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q5T4F7

Overview

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.

Molecular Function

PDZ domain binding, Wnt-protein binding, Wnt-activated receptor activity

Subcellular Location

Secreted

Expression

Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle.

Alternative Nomenclature

Frizzled related protein 1b

FRP 1b

SARP3

Secreted apoptosis related protein 3

Secreted frizzled related protein 5