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General Information
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Product
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Shade Peptide
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Description
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Antigenic Blocking Peptide Shade, isoform B Antibody N-epitope
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Verified Applications
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Immunocompetition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 1-50 on Ecdysone 20-monooxygenase (SHADE) protein.
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Accession #
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NCBI: NP_996074.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9VUF8
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Overview
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Required for CNS development; midline glial cells. Involved in the metabolism of insect hormones; responsible for all ecdysone 20-monooxygenase activity during embryonic, larval and adult stages. May be involved in the breakdown of synthetic insecticides.
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Molecular Function
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Monooxygenase, Oxidoreductase
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Subcellular Location
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Mitochondrion membrane
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Expression
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Strong expression by embryonic stage 10 in epidermis, decreases significantly in older embryos. Third instar larvae show expression in the midgut copper cells, Malpighian tubules and fat body. In the adult ovaries, expression is seen in both nurse cells a
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Structure
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Belongs to the cytochrome P450 family.
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Alternative Nomenclature
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SH2 domain-containing adapter protein D antibody
SHD antibody
Src homology 2 domain containing transforming protein D antibody Ecdysone 20-monooxygenase
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SHD / Shade Antibody
Shade Antibody FITC
Shade Antibody BIOTIN
Shade Positive Control
