Synaptophysin Blocking Peptide

General Information

Product

Synaptophysin Peptide N-epitope

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic peptide taken within amino acid region 1-100 on human Synaptophysin protein.

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P08247

Overview

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).

Molecular Function

Cholesterol binding, protein self-association, transporter  activity

Subcellular Location

Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane; Multi-pass membrane protein. Cell junction ›synapse › synaptosome

Expression

Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.

Structure

Homohexamer or homotetramer. Interacts with SRCIN1.

Alternative Nomenclature

Major synaptic vesicle protein P38 antibody

MRXSYP antibody

Syn p38 antibody

Synaptophysin antibody

SYP antibody

SYPH antibody

SypI antibody