Src Blocking Peptide

General Information

Product

Src Peptide

Description

Antigenic Blocking Peptide Proto-oncogene tyrosine-protein kinase Src C-epitope

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic peptide taken within amino acid region 400-500 on human Src protein.

Accession #

NCBI:  NP_005408.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P12931

Overview

Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis migration, and transformation.

Molecular Function

ATP binding, ephrin receptor binding, heme binding, ion channel binding, enzyme binding, growth factor receptor binding, integrin binding, kinase activity

Subcellular Location

Cell membrane, mitochondrion inner membrane, nucleus, cytoplasm (Note: Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and SH3 domain.)

Expression

Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues.

Structure

Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.

Contains 1 protein kinase domain.

Contains 1 SH2 domain.

Contains 1 SH3 domain.

Alternative Nomenclature

ASV antibody

Avian sarcoma virus antibody

c SRC antibody

CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody

EC 2.7.10.2 antibody

Neuronal CSRC tyrosine specific protein kinase antibody

Neuronal SRC antibody

Oncogene SRC antibody

p60 Src antibody

Proto-oncogene tyrosine-protein kinase Src antibody

SRC proto oncogene non receptor tyrosine kinase antibody

SRC1 antibody

Tyrosine kinase pp60c src antibody

Tyrosine protein kinase SRC1 antibody

v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody