General Information |
|
Product |
Src Peptide |
Description |
Antigenic Blocking Peptide Proto-oncogene tyrosine-protein kinase Src C-epitope |
Verified Applications |
Immunocompetition, Immunodepletion |
Peptide Description |
Synthetic peptide taken within amino acid region 400-500 on human Src protein. |
Accession # |
NCBI: NP_005408.1 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis migration, and transformation. |
Molecular Function |
ATP binding, ephrin receptor binding, heme binding, ion channel binding, enzyme binding, growth factor receptor binding, integrin binding, kinase activity |
Subcellular Location |
Cell membrane, mitochondrion inner membrane, nucleus, cytoplasm (Note: Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and SH3 domain.) |
Expression |
Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues. |
Structure |
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. Contains 1 protein kinase domain. Contains 1 SH2 domain. Contains 1 SH3 domain. |
Alternative Nomenclature |
ASV antibody Avian sarcoma virus antibody c SRC antibody CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody EC 2.7.10.2 antibody Neuronal CSRC tyrosine specific protein kinase antibody Neuronal SRC antibody Oncogene SRC antibody p60 Src antibody Proto-oncogene tyrosine-protein kinase Src antibody SRC proto oncogene non receptor tyrosine kinase antibody SRC1 antibody Tyrosine kinase pp60c src antibody Tyrosine protein kinase SRC1 antibody v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
Src-112AP | |||
|
Src.112-FITC | |||
|
Src.112-BIOTIN | |||
|
PC-SRC | |||
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