EpCAM Blocking Peptide

General Information

Product

EpCAM Peptide

Description

Antigenic Blocking Peptide Tumor-associated Calcium signal transducer 1, isoform CRA_b Antibody N-epitope

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic Peptide

Accession #

GenBank: EAX00219.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

UPI0000EE24A7

Overview

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Molecular Function

Tumor antigen

Subcellular Location

Cell junction, Cell membrane, Membrane, Tight junction

Expression

Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal

Structure

Belongs to EPCAM family.  Contains 1 thryoglobulin type-1 domain.

Alternative Nomenclature

17 1A antibody

323/A3 antibody

Adenocarcinoma associated antigen antibody

Antigen identified by monoclonal antibody AUA1 antibody

CD326 antibody

Cell surface glycoprotein Trop 1 antibody

Cell surface glycoprotein Trop 2 antibody

CO17 1A antibody

DIAR5 antibody

EGP antibody

EGP2 antibody

EGP314 antibody

EGP40 antibody

Ep CAM antibody

Epithelial cell adhesion molecule antibody

Epithelial glycoprotein 1 antibody

Epithelial glycoprotein 314 antibody

ESA antibody

GA733 1 antibody

GA733 2 antibody

gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody

HNPCC8 antibody

Human epithelial glycoprotein 2 antibody

KS 1/4 antigen antibody

KSA antibody

Lymphocyte antigen 74 antibody

M1S 1 antibody

M1S2 antibody

M4S1 antibody

Major gastrointestinal tumor associated protein GA733 2 antibody

Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody

MIC18 antibody

MK 1 antibody

TACD1 antibody

TACSTD1 antibody

TROP1 antibody

Tumor associated calcium signal transducer 1 antibody

Tumor associated calcium signal transducer 2 precursor antibody