EpCAM Antibody

Product no.: TACSTD1-101AP

$285.00

Description

General Information
Product	EpCAM Antibody
Description	Affinity Purified Tumor-associated Calcium signal transducer 1 Antibody N-epitope
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Human
Immunogen	N-epitope specific synthetic peptide taken within amino acid region 100-200 on human Tumor-associated calcium signal transducer 1 protein.
Accession #	GenBank: EAX00219.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55-0.78 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
DOT Blot	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	UPI0000EE24A7
Overview	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Molecular Function	Tumor antigen
Subcellular Location	Cell junction, Cell membrane, Membrane, Tight junction
Expression	Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
Structure	Belongs to EPCAM family. Contains 1 thryoglobulin type-1 domain.
Alternative Nomenclature	17 1A antibody 323/A3 antibody Adenocarcinoma associated antigen antibody Antigen identified by monoclonal antibody AUA1 antibody CD326 antibody Cell surface glycoprotein Trop 1 antibody Cell surface glycoprotein Trop 2 antibody CO17 1A antibody DIAR5 antibody EGP antibody EGP2 antibody EGP314 antibody EGP40 antibody Ep CAM antibody Epithelial cell adhesion molecule antibody Epithelial glycoprotein 314 antibody ESA antibody GA733 1 antibody gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody HNPCC8 antibody Human epithelial glycoprotein 2 antibody KS 1/4 antigen antibody KSA antibody Lymphocyte antigen 74 antibody M1S 1 antibody M1S2 antibody M4S1 antibody Major gastrointestinal tumor associated protein GA733 2 antibody Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody MIC18 antibody MK 1 antibody TACD1 antibody TROP1 antibody Tumor associated calcium signal transducer 1 antibody Tumor associated calcium signal transducer 2 precursor antibody

Protein information supplied by UniProt