TRAF6 Blocking Peptide

General Information

Product

TRAF6 Peptide

Description

Antigenic Blocking Peptide TNF receptor-associated factor 6 Antibody

Verified Applications

Immunocompeition, Immunodepletion

Peptide Description

Synthetic Peptide

Accession #

NCBI:  NP_665802.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q9Y4K3

Overview

Mediates synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, may be essential for formation of functional osteoclasts, seems to also play a role in dendritic cells maturation and/or activation.

Molecular Function

histone deacetylase binding, ligase activity, zinc ion binding, protein kindase B binding, protein N-terminus binding signal transducer activity

Subcellular Location

Cytoplasm, cell cortex, nucleus, lipid droplet. (Note: Found in nuclei of some aggressive B-cell lymphoma cell lines as well as in the nuclei of both resting and activated T- and B-lymphocytes. Found in punctate nuclear body protein complexes. Ubiquitinat

Expression

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Alternative Nomenclature

E3 ubiquitin-protein ligase TRAF6 antibody

Interleukin 1 signal transducer antibody

RING finger protein 85 antibody

RNF85 antibody

TNF receptor-associated factor 6, E3 ubiquitin protein ligase antibody