AMPK alpha 1 Positive Control

Product no.: PC-AMPK1

$200.00

Description

General Information
Product	AMPK alpha 1 Positive Control
Description	Western Blot Positive Control 5'-AMP-activated protein kinase catalytic subunit alpha-1
Verified Applications	WB
Immunogen	Purified Protein
Physical Properties
Quantity	5 Applications
Volume	Inquire
Form	Western Blot Positive Control
Storage	-20⁰C for long term storage
Application Protocol
Western Blot	1:2,500-1:5,000
Protein
Uniprot #	P54645
Overview	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.
Molecular Function	[acetyl-CoA carboxylase] kinase activity [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity AMP-activated protein kinase activity ATP binding chromatin binding eukaryotic elongation factor-2 kinase activator activity g
Subcellular Location	Nucleus, Cytoplasm
Expression	Low expression in kidney, liver, lung, heart and brain.
Structure	The AIS (autoinhibitory sequence) region shows some sequence similarity with the ubiquitin-associated domains and represses kinase activity.
Alternative Nomenclature	5 AMP activated protein kinase alpha 1catalytic subunit antibody AAPK1 antibody ACACA kinase antibody acetyl CoA carboxylase kinase antibody AMP -activate kinase alpha 1 subunit antibody AMPK 1 antibody AMPK alpha 1 antibody HMG CoA reductase kinase antibody HMGCR kinase antibody hormone sensitive lipase kinase antibody Hydroxymethylglutaryl CoA reductase kinase antibody im:7154392 antibody kinase AMPK alpha1 antibody PRKAA 1 antibody Protein kinase AMP activated alpha 1 catalytic subunit antibody SNF1A antibody Tau protein kinase PRKAA1 antibody

Protein information supplied by UniProt.