Apelin Receptor Positive Control

General Information

Product

Apelin Receptor Positive Control

Verified Applications

WB

Immunogen

Purified protein.

Accession #

NCBI:  NP_005152

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

P35414

Overview

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Molecular Function

Developmental protein, G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Multi-pass membrane protein

Expression

Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

Structure

Transmembrane, Transmembrane helix

Alternative Nomenclature

AGTRL1 ligand antibody

APEL antibody

Apelin-13 antibody

APJ endogenous ligand antibody

Apln antibody

XNPEP2 antibody