Inhibin alpha Positive Control

General Information

Product

Inhibin alpha Positive Control

Description

Western Blot Positive Control Inhibin alpha chain; Flags 

Verified Applications

WB

Immunogen

Purified Protein

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

P05111

Overview

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone.

Molecular Function

Cytokine activity, hormone activity, growth factor activity, receptor binding

Subcellular Location

Secreted

Expression

Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.

Alternative Nomenclature

A inhibin subunit precursor antibody

IHA antibody

inhA antibody

Inhibin alpha chain antibody

Inhibin alpha chain precursor antibody