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General Information
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Product
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KIRREL / Neph1 Positive Control
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Description
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Western Blot Positive Control Kin of IRRE-like protein 1
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Verified Applications
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WB
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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| Concentration |
The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel. |
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Protein
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Uniprot #
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Q80W68
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Overview
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Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.
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Molecular Function
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Myosin Binding
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Subcellular Location
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Cell membrane; Single-pass type I membrane protein
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Expression
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Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli.
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Structure
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Interacts with TJP1/ZO-1 and with NPHS2/podocin (via the C-terminus). Interacts with NPHS1/nephrin (via the Ig-like domains); this interaction is dependent on KIRREL glycosylation. Homodimer (via the Ig-like domains). Interacts when tyrosine-phosphorylate
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Alternative Nomenclature
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FLJ10845 antibody
Kin of IRRE like (Drosophila) antibody
Kin of IRRE like antibody
Kin of irregular chiasm-like protein 1 antibody
Kirrel antibody
MGC129542 antibody
MGC129543 antibody
NEPH 1 antibody
Nephrin like protein 1 antibody
Nephrin related antibody
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KIRREL Antibody
KIRREL Antibody
KIRREL Antibody FITC
KIRREL Antibody BIOTIN
KIRREL Blocking Peptide
KIRREL Antibody BIOTIN
KIRREL Blocking Peptide
KIRREL Blocking Peptide
KIRREL Antibody
KIRREL Antibody FITC
KIRREL Antibody FITC
KIRREL Antibody BIOTIN
