PGCA Positive Control

Product no.: PC-PGCA

$220.00

Description
Publications

General Information
Product	PGCA Positive Control
Description	Western Blot Positive Control Atrial natriuretic peptide receptor 1
Verified Applications	WB
Physical Properties
Quantity	5 Applications
Volume	Inquire
Concentration	The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel.
Form	Western Blot Positive Control
Storage	-20⁰C for long term storage

Protein
Uniprot #	P16066
Overview	Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Molecular Function	ATP binding, GTP binding, hormone binding, Protein kinase activity, G-protein coupled peptide receptor activity
Subcellular Location	Membrane; Single-pass type I membrane protein
Structure	Homodimer
Alternative Nomenclature	ANP A antibody Atrial natriuretic peptide A type receptor antibody Atrial natriuretic peptide receptor 1 antibody GC A antibody GC-A antibody Guanylate cyclase A antibody NPR 1 antibody NPR A antibody

Protein information supplied by UniProt

Fabgennix PGCA-101AP Antibody has been used in 11 Publications

Thompson, Iain R. et al. “Homologous and Heterologous Desensitization of Guanylyl Cyclase-B Signaling in GH3 Somatolactotropes.” Cell and Tissue Research 355.2 (2014): 425–436. PMC3921447

Confocal Microscopy, Immunofluorescence; Human, Rat

Watson, Chris J et al. “Mechanical Stretch up-Regulates the B-Type Natriuretic Peptide System in Human Cardiac Fibroblasts: a Possible Defense Against Transforming Growth Factor-β Mediated Fibrosis.”Fibrogenesis & Tissue Repair 5 (2012): 9. PMC3411484

Confocal Microscopy, Immunofluorescence,Western Blot; Human

D. Muller, et. al. "Cylic GMP signaling in rat urinary bladder, prostate, and epidiymis: tissue-specific changes with aging and in response to Leydig cell depletion." Journal Society for Reproduction Fertility. 2011 April; 10.1530 PMID21511885

Western Blot; Rat

Kotlo, Kumar U., Mark M. Rasenick, and Robert S. Danziger. “Evidence for Cross-Talk Between Atrial Natriuretic Peptide and Nitric Oxide Receptors.”Molecular and cellular biochemistry 338.1-2 (2010): 183–189. PMC2863078

Confocal Microscopy Immunofluorescence, Immunoprecipitation, Western Blot; Human

Müller, Dieter, et al. "The Membrane Receptors Guanylyl Cyclase-A And -B Undergo Distinctive Changes In Post-Translational Modification During Brain Development D. Müller Et Al. Guanylyl Cyclase-A And -B Glycosylation In Brain." Journal Of Neurochemistry 115.4 (2010): 1024-1034. PMID20880010

Western Blot; Mouse, Rat

Liu, Cambrian Y., Scott E. Fraser, and David S. Koos. "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." Journal of Comparative Neurology 516.1 (2009): 36-48.PMID19565523

Immunofluorescence, Western Blot; Mouse

Thompson, Iain R., et al. "Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, αT3-1 and LβT2 gonadotroph cells." Journal of Endocrinology 203.2 (2009): 215-229. PMID19666697

Western Blot; Mouse

Chen, Songcang et al. “Tonicity-Dependent Induction of Sgk1 Expression Has a Potential Role in Dehydration-Induced Natriuresis in Rodents.”The Journal of Clinical Investigation 119.6 (2009): 1647–1658. PMC2689130

Western Blot; Mouse, Rat

Guo, Dagang et al. “A New Rac-cGMP Signaling Pathway.” Cell 128.2 (2007): 341–355. PMC1965458

Immunoprecipitation, Western Blot; Mouse

Madhusoodanan, K. S. et al. “Csk Mediates G Protein-Coupled Lysophosphatidic Acid Receptor-Induced Inhibition of Membrane-Bound Guanylyl Cyclase Activity.” Biochemistry 45.10 (2006): 3396–3403.

PMC2519153

Immunoprecipitation; Human

Zhu, Bing, Samuel Strada, and Troy Stevens. "Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells." American Journal of Physiology-Lung Cellular and Molecular Physiology 289.2 (2005): L196-L206. PMID15792963

Immunoprecipitation, Western Blot; Rat

Publishing research using PGCA-101AP? Please let us know, we can cite the reference in this datasheet.