MASPIN Positive Control

General Information

Product

MASPIN Positive Control

Description

Western Blot Positive Control Serpin B5

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_002630.2

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

P36952

Overview

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Molecular Function

Serine-type endopeptidase inhibitor activity

Subcellular Location

Secreted > extracellular space

Expression

Normal mammary epithelial cells.

Structure

Interacts with IRF6.

Alternative Nomenclature

mammary serine proteinase inhibitor antibody

Maspin antibody

Peptidase inhibitor 5 antibody

Protease inhibitor 5 antibody

Serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody

SERPINB5 antibody