MASPIN Antibody

Product no.: SPB5-112AP

$285.00

General Information
Product	MASPIN Antibody
Description	Affinity Purified Serpin B5 Antibody C-epitope
Verified Applications	CM, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 310-360 on human MASPIN protein.
Accession #	GenBank: AAA18957.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.50 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunofluorescence	1:200
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	P36952
Overview	Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Molecular Function	Serine-type endopeptidase inhibitor activity
Subcellular Location	Secreted > extracellular space
Expression	Normal mammary epithelial cells.
Structure	Interacts with IRF6.
Alternative Nomenclature	mammary serine proteinase inhibitor antibody Maspin antibody Peptidase inhibitor 5 antibody Protease inhibitor 5 antibody Serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody SERPINB5 antibody

Protein information supplied by UniProt