General Information
|
|
Product
|
MASPIN Antibody
|
Description
|
Affinity Purified Serpin B5 Antibody C-epitope
|
Verified Applications
|
CM, ELISA, ICC, IF, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 310-360 on human MASPIN protein.
|
Accession #
|
GenBank: AAA18957.1
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.50 µg/µl in antibody stabilization buffer
|
Form
|
Affinity Purified
|
Clonality
|
Polyclonal
|
Determinant
|
C-epitope
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunohistochemistry |
1:50-1:150 |
Immunofluorescence
|
1:200
|
Immunoprecipitation
|
1:150
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P36952
|
Overview
|
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
|
Molecular Function
|
Serine-type endopeptidase inhibitor activity
|
Subcellular Location
|
Secreted > extracellular space
|
Expression
|
Normal mammary epithelial cells.
|
Structure
|
Interacts with IRF6.
|
Alternative Nomenclature
|
mammary serine proteinase inhibitor antibody
Maspin antibody
Peptidase inhibitor 5 antibody
Protease inhibitor 5 antibody
Serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody
SERPINB5 antibody
|
|
|