TLR10 Positive Control

General Information

Product

TLR10 Positive Control

Description

Western Blot Positive Control Toll-like receptor 10

Verified Applications

WB

Immunogen

Purified Protein

Accession #

GenBank: AAQ88667.1

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q9BXR5

Overview

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Molecular Function

Receptor, transmembrane signaling receptor activity

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

Structure

Binds MYD88 via their respective TIR domains (By similarity). Homodimer (Potential).

Alternative Nomenclature

CD 290 antibody

CD 290 antigen antibody

MGC104967 antibody

MGC126398 antibody

MGC126399 antibody

OTTHUMP00000158729 antibody

OTTHUMP00000218162 antibody

TLR10 antibody

Toll like receptor 10 antibody

UNQ315/PRO358 antibody