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General Information
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Product
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TLR10 Antibody
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Description
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Affinity Purified Toll-like receptor 10 Antibody
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Verified Applications
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ELISA, ICC, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Chimpanzee, Human, Monkey, Pig, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 380-430 on human TLR10 protein.
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Accession #
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GenBank: AAQ88667.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.67 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:20,000
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Immunocytochemistry
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1:100
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Immunofluorescence
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1:100
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Immunohistochemistry
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1:100
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9BXR5
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Overview
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Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
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Molecular Function
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Receptor, transmembrane signaling receptor activity
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Subcellular Location
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Membrane; Single-pass type I membrane protein
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Expression
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Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
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Structure
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Binds MYD88 via their respective TIR domains (By similarity). Homodimer (Potential).
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Alternative Nomenclature
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CD 290 antibody
CD 290 antigen antibody
TLR10 antibody
Toll like receptor 10 antibody
UNQ315/PRO358 antibody
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TLR10 Antibody FITC
TLR10 Antibody BIOTIN
TLR10 Blocking Peptide
TLR10 Positive Control
