General Information |
|
Product |
Phospho-Chimaerin beta 2 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Phosphorylated N-Chimaerin isoform 1 Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Phosphorylated synthetic peptide corresponding to unique amino acid sequence on beta 2 Chimaerin protein. |
Accession # |
NCBI: NP_001813 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.58-0.63 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
0 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
0 |
Immunohistochemistry |
0 |
Immunoprecipitation |
0 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. |
Molecular Function |
GTPase activation |
Subcellular Location |
Cytosol |
Expression |
In neurons in brain regions that are involved in learning and memory processes. |
Structure |
Interacts with EPHA4; effector of EPHA4 in axon guidance linking EPHA4 activation to RAC1 regulation. |
Alternative Nomenclature |
A-chimaerin antibody ARHGAP2 antibody CHN antibody Chn1 antibody N chimaerin antibody NC antibody Rho GTPase-activating protein 2 antibody RHOGAP2 antibody |
Protein information supplied by UniProt
Fabgennix Phospho Chimaerin beta 2 Antibody has been used in 1 Publication |
|
Griner, Erin M. et al. “A Novel Cross-Talk in Diacylglycerol Signaling: THE RAC-GAP Β2-CHIMAERIN IS NEGATIVELY REGULATED BY PROTEIN KINASE Cδ-MEDIATED PHOSPHORYLATION.” The Journal of Biological Chemistry 285.22 (2010): 16931–16941. PMC2878072
|
Western Blot; Human |
Publishing research using PCHIM-140AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
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PCHIM-140AP | |||
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P-PCHIM | |||
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PCHIM-BIOTIN | |||
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PC-PCHIM | |||
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