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General Information
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Product
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PDE10A2 Antibody
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Description
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Affinity Purified Phosphodiesterase 10A2 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Rat
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Immunogen
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Synthetic peptide taken within amino acid region 1-50 on human PDE10A2 protein.
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Accession #
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GenBank: AAD32596.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9Y233
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Overview
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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
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Molecular Function
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Hydrolase, metal-ion binding, cGMP binding
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Subcellular Location
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Cytoplasm
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Expression
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Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
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Structure
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Homodimer
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Alternative Nomenclature
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5''-cyclic phosphodiesterase 10A antibody
cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A antibody
cAMP and cAMP-inhibited cGMP 3'' antibody
FLJ11894 antibody
HSPDE10A antibody
Phosphodiesterase 10A antibody
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PDE10A2 Antibody FITC
PDE10A2 Antibody BIOTIN
PDE10A2 Blocking Peptide
PDE10A2 Positive Control
