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General Information
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Product
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Phospho-PDE10A Antibody
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Description
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Affinity Purified Phosphorylated Phosphodiesterase 10A Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Phosphorylated synthetic MAP common to all PDE10A variants. Taken within amino acid region 1-50 on human PDE10A protein.
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| Specificity |
This antibody will detect only phosphorylated PDE10A protein. |
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Accession #
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GenBank: AAD32596.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.7 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9Y233
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Overview
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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
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Molecular Function
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Hydrolase, metal-ion binding, cGMP binding
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Subcellular Location
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Cytoplasm
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Expression
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Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
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Structure
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Homodimer
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Alternative Nomenclature
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5''-cyclic phosphodiesterase 10A antibody
cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A antibody
FLJ11894 antibody
HSPDE10A antibody
PDE 10A antibody
Pde10a antibody
Phosphodiesterase 10A antibody
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Phospho-PDE10A Antibody FITC
Phospho-PDE10A Antibody BIOTIN
Phospho-PDE10A Blocking Peptide
Phospho-PDE10A Positive Control
