PDE2A Antibody FITC

General Information

Product

Pan PDE2A Antibody FITC-Conjugated

Description

FITC-Conjugated Phosphodiesterase 2A, cGMP-stimulated Antibody C-epitope

Verified Applications

CM, ELISA, FRET, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique C-terminal amino acid sequence on PDE2A gene.

Accession #

GenBank: EAW74861.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

FITC-Conjugated

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250-1:1,000

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250-1:1,000

Immunofluorescence

1:150-1:1,000

Immunohistochemistry

1:250-1:1,000

Immunoprecipitation

1:200

Western Blot

1:250-1:1,000

Protein

Uniprot #

UPI000003B340

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Molecular Function

Hydrolase, cAMP, cGMP, Metal-binding, Angiogenesis

Subcellular Location

Multi-pass membrane protein

Expression

bundant in adipose tissues.

Structure

Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6.

Alternative Nomenclature

5''-cyclic phosphodiesterase antibody

cGMP dependent 3'5' cyclic phosphodiesterase antibody

cGMP stimulated phosphodiesterase 1 antibody

cGMP stimulated phosphodiesterase 4 antibody

cGMP-dependent 3'' antibody

CGS PDE antibody

Cyclic GMP stimulated phosphodiesterase antibody

PDE 2A antibody

PDE 2A1 antibody

PDE 2A4 antibody

PDE2A antibody

Phosphodiesterase 2A cGMP stimulated antibody