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General Information
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Product
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Phospho Slingshot homolog 1 Antibody
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Description
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Affinity Purified Phosphorylated Protein phosphatase Slingshot homolog 1 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Phosphorylated synthetic peptide corresponding to unique amino acid sequence on Slingshot homolog 1 protein.
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Accession #
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NCBI: NP_061857.3
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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Q8WYL5
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Overview
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Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
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Molecular Function
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Hydrolase, protein phosphatase
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Subcellular Location
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Cytoplasm, cytoskeleton, cell projection, lamellipodium, cleavage furrow, midbody. (Note: Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at site of cell locomotion.
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Alternative Nomenclature
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AW551225 antibody
Coro1c antibody
coronin, actin binding protein 1C antibody
Gm1394 antibody
Gm1395 antibody
Protein phosphatase Slingshot homolog 1 antibody
slingshot like 1 antibody
SSH1 antibody
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Phospho-Slingshot homolog 1 Antibody FITC
Phospho-Slingshot homolog 1 Antibody BIOTIN
Phospho-Slingshot homolog 1 Blocking Peptide
Phospho-Slingshot homolog 1 Positive Control
