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General Information
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Product
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Phospho trp Antibody Affinity Purified
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Description
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Affinity Purified Phosphorylated Transient Receptor Potential isoform A Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Drosophila melanogaster
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Immunogen
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Phosphorylated synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Transient Receptor Potential isoform A protein.
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Accession #
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NCBI: NP_476768.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.6 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:10,000
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Protein
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Uniprot #
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P19334
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Overview
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A light-sensitive calcium channel that is required for inositide-mediated Ca2+ entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca2+ influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling.
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Molecular Function
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Calcium channel, Ion channel, Calmodulin activity
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Subcellular Location
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Cell membrane; Multi-pass membrane protein
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Expression
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Expressed predominantly in the rhabdomeres of photoreceptor cells. Expressed in the third antennal segment and in the olfactory segment at approximately 70 hours after puparium formation during antennal development.
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Structure
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The C-terminus interacts with a PDZ domain of inaD to form the core of the inaD signaling complex. Other members of the complex include norpA (PLC), inaC (PKC), and possibly trpl, ninaC, FKBP59, calmodulin and rhodopsin. Forms homomultimers and heteromult
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Alternative Nomenclature
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DmTRP antibody
dTRP antibody
Transient receptor potential antibody
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Phospho-trp Antibody FITC
Phospho-trp Antibody BIOTIN
Phospho-trp Blocking Peptide
Phospho-trp Positive Control
