SorLA Antibody


SorLA Antibody

Product no.: SORLA-101AP
$295.00
$265.00


General Information

 

 

Product

 

SorLA Antibody

Description

Affinity Purified Sortilin-related receptor Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 2100-2200 on human SORLA receptor protein.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.50-0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunohistochemistry 1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:500


Protein

 

Uniprot #

 

O88307

Overview

Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems.

Molecular Function

beta-amyloid binding, low-density lipoprotein particle binding

Subcellular Location

membrane, single-pass type I membrane protein, golgi apparatus, secreted

Expression

Abundant in brain, where it is mainly expressed in adult cerebellum, hippocampal ca regions, dentate gyrus, and to a much lesser extent in the cerebral cortex. Detectable in kidney, skeletal muscle, lung and spleen, but not in the liver.

Alternative Nomenclature

C11orf32 antibody

gp250 antibody

LDLR relative with 11 ligand binding repeats antibody

Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody

LR11 antibody

LRP9 antibody

Mosaic protein LR11 antibody

SORL1 antibody

SorLA 1 antibody

Sortilin related receptor antibody

Sorting protein related receptor containing LDLR class A repeats antibody

Sorting protein-related receptor containing

   

Protein information supplied by UniProt

Accessories

Product Note Status Price
SorLA Antibody FITC SorLA Antibody FITC
SORLA-FITC $350.00 *
SorLA Antibody BIOTIN SorLA Antibody BIOTIN
SORLA-BIOTIN $350.00 *
SorLA Blocking Peptide SorLA Blocking Peptide
P-SORLA $145.00 *
SorLA Positive Control SorLA Positive Control
PC-SORLA $185.00 *
Display accessory details

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