General Information
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Product
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SOX10 Antibody
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Description
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Affinity Purified Transcription Factor SOX-10 Antibody C-epitope
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 400-450 on human Transcription Factor SOX-10 protein.
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Accession #
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NCBI: NP_008872.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P56693
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Overview
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Transcription factor that seems to function synergistically with the POU domain protein TST-1/OCT6/SCIP. Could confer cell specificity to the function of other transcription factors in developing and mature glia.
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Molecular Function
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Chromatin binding; Identical protein binding; RNA polymerase II transcription factor binding transcription factor activity invovled in positive regulation of transcription.
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Subcellular Location
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Cytoplasm; Nucleus
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Expression
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Expressed in fetal brain and in adult brain, heart, small intestine and colon.
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Structure
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Contains 1 HMG box DNA-binding domain.
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Alternative Nomenclature
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DOM
MGC15649
PCWH
SOX 10
SRY (sex determining region Y) box 10
SRY related HMG box gene 10
Transcription factor SOX 10
WS2E
WS4
WS4C
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