VPS26 Antibody

Product no.: VPS26-101AP

$285.00

Description

General Information
Product	VPS26 Antibody
Description	Affinity Purified Vacuolar protein sorting-associated protein 26A Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acids 315-375 on human VPS26 protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.56 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:200
Immunohistochemistry	1:100
Western Blot	1:500
Protein
Uniprot #	O75436
Overview	Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.
Molecular Function	protein transporter activity
Subcellular Location	cytoplasm, endosome membrane, preipheral membrane protein (Note: Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes)
Expression	Down-regulated in Alzheimer disease. No polymorphism or variant is however associated with Alzheimer disease for VPS26A.
Alternative Nomenclature	FLJ12930 antibody FLJ12930 antibody HB 58 antibody Hbeta 58 antibody Hbeta 58 homolog antibody MGC94168 antibody PEP 8A antibody Vacuolar protein sorting 26 A antibody Vacuolar protein sorting 26 homolog A yeast antibody Vacuolar protein sorting associated protein 26A antibody Vesicle protein sorting 26A antibody VPS 26 antibody VPS 26A antibody

Protein information supplied by UniProt