|
General Information
|
|
|
Product
|
VPS26 Antibody
|
|
Description
|
Affinity Purified Vacuolar protein sorting-associated protein 26A Antibody
|
|
Verified Applications
|
ELISA, IHC, IP, WB
|
|
Host
|
Rabbit
|
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
|
Immunogen
|
Synthetic peptide taken within amino acids 315-375 on human VPS26 protein.
|
|
Physical Properties
|
|
|
Quantity
|
100 µg
|
|
Volume
|
200 µl
|
|
Concentration
|
0.56 µg/µl in antibody stabilization buffer
|
|
Form
|
Affinity Purified
|
|
Clonality
|
Polyclonal
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
DB
|
1:10,000
|
|
ELISA
|
1:10,000
|
| Immunoprecipitation |
1:200 |
| Immunohistochemistry |
1:100 |
|
Western Blot
|
1:500
|
|
Protein
|
|
Uniprot #
|
O75436
|
|
Overview
|
Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.
|
|
Molecular Function
|
protein transporter activity
|
|
Subcellular Location
|
cytoplasm, endosome membrane, preipheral membrane protein (Note: Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes)
|
|
Expression
|
Down-regulated in Alzheimer disease. No polymorphism or variant is however associated with Alzheimer disease for VPS26A.
|
|
Alternative Nomenclature
|
FLJ12930 antibody
FLJ12930 antibody
HB 58 antibody
Hbeta 58 antibody
Hbeta 58 homolog antibody
MGC94168 antibody
PEP 8A antibody
Vacuolar protein sorting 26 A antibody
Vacuolar protein sorting 26 homolog A yeast antibody
Vacuolar protein sorting associated protein 26A antibody
Vesicle protein sorting 26A antibody
VPS 26 antibody
VPS 26A antibody
|
| |
|
VPS26 Antibody FITC
VPS26 Antibody BIOTIN
VPS26 Blocking Peptide
VPS26 Positive Control
