General Information

Product

CD4 Antibody

Description

Affinity Purified T-cell surface glycoprotein CD4 isoform 1 precursor Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse

Immunogen

Synthetic peptide taken within amino acid region 270-320 on human CD4 protein.

Accession #

NCBI:  NP_000607.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P01730

Overview

Accesory protein for MHC class-II antigen/T-cell receptor interaction.

Molecular Function

Adaptive Immunity; Host-virus interaction; Immunity

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Structure

Contains 3 Ig-like C2-type domains; Contains 1 Ig-like V-type domain

Alternative Nomenclature

CD 4 antibody

CD4 (L3T4) antibody

CD4 antigen (p55) antibody

CD4 antigen antibody

CD4 molecule antibody

CD4 receptor antibody

CD4+ Lymphocyte deficiency, included antibody

CD4mut antibody

L3T4 antibody

Leu3 antibody

Ly-4 antibody

Lymphocyte antigen CD4 antibody

p55 antibody

T cell differentiation antigen L3T4 antibody

T cell OKT4 deficiency, included antibody

T-cell surface antigen T4/Leu-3 antibody

T-cell surface glycoprotein CD4 antibody

W3/25 antigen antibody

General Information

Product

CD4 Antibody

Description

Affinity Purified T-cell surface glycoprotein CD4 Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide corresponding to Human CD4 aa 437-458 (C terminal). The selected peptide was post-synthetically modified to achieve highest antigenicity before couplingto carrier protein using hetero bifunctional cross linker for Immunogen preparation.

Sequence:

RLLSEKKTCQCPHRFQKTCSPI

Accession #

NCBI:  NP_000607.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500. Predicted Molecular weight: 51 kDa

CD4-112AP labels a band of 28 kDa, the identity of this band is not fully understood, but may represent a proteolytic degradation product of CD4.

Protein

Uniprot #

P01730

Overview

Accesory protein for MHC class-II antigen/T-cell receptor interaction.

Molecular Function

Adaptive Immunity; Host-virus interaction; Immunity

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Structure

Contains 3 Ig-like C2-type domains; Contains 1 Ig-like V-type domain

Alternative Nomenclature

CD 4 antibody

CD4 (L3T4) antibody

CD4 antigen (p55) antibody

CD4 antigen antibody

CD4 molecule antibody

CD4 receptor antibody

CD4+ Lymphocyte deficiency, included antibody

CD4mut antibody

L3T4 antibody

Leu3 antibody

Ly-4 antibody

Lymphocyte antigen CD4 antibody

p55 antibody

T cell differentiation antigen L3T4 antibody

T cell OKT4 deficiency, included antibody

T-cell surface antigen T4/Leu-3 antibody

T-cell surface glycoprotein CD4 antibody

W3/25 antigen antibody

General Information

Product

Granzyme B Antibod

Description

Affinity Purified Granzyme B Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human endogenous Granzyme B protein.

Accession #

GenBank:  AAR23323.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P10144

Overview

This enzyme is necessary for target cell lysis in cell-mediated immune responses;Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Molecular Function

Hydrolase, Protease, Serine protease

Subcellular Location

intracellular membrane-bounded organelle;nucleus;cytoplasm

Expression

leukocyte;adipose tissue;appendix;bladder;bone marrow;colon;duodenum;endometrium

Alternative Nomenclature

C11 antibody

Cathepsin G like 1 antibody

CCPI antibody

CGL 1 antibody

CSP B antibody

CTLA 1 antibody

CTSGL 1 antibody

Cytotoxic serine protease B antibody

Cytotoxic T Lymphocyte Associated Serine Esterase 1 antibody

Cytotoxic T lymphocyte proteinase 2 antibody

Fragmentin 2 antibody

Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) antibody

Granzyme-2 antibody

GRB antibody

GZMB antibody

HLP antibody

Human lymphocyte protein antibody

Lymphocyte protease antibody

Protease Serine B antibody

SECT antibody

T-cell serine protease 1-3E antibody

General Information

Product

Granzyme B Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human endogenous Granzyme B protein.

Accession #

GenBank:  AAR23323.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P10144

Overview

This enzyme is necessary for target cell lysis in cell-mediated immune responses;Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Molecular Function

Hydrolase, Protease, Serine protease

Subcellular Location

intracellular membrane-bounded organelle; nucleus; cytoplasm

Expression

leukocyte; adipose tissue; appendix; bladder; bone marrow; colon; duodenum; endometrium

Alternative Nomenclature

C11 antibody

Cathepsin G like 1 antibody

CCPI antibody

CGL 1 antibody

CSP B antibody

CTLA 1 antibody

CTSGL 1 antibody

Cytotoxic serine protease B antibody

Cytotoxic T Lymphocyte Associated Serine Esterase 1 antibody

Cytotoxic T lymphocyte proteinase 2 antibody

Fragmentin 2 antibody

Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) antibody

Granzyme-2 antibody

GRB antibody

GZMB antibody

HLP antibody

Human lymphocyte protein antibody

Lymphocyte protease antibody

Protease Serine B antibody

SECT antibody

T-cell serine protease 1-3E antibody

General Information

Product

TIA1 Antibody Affinity Purified

Description

Affinity Purified Nucleolysin TIA-1 isoform p40 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human TIA1 protein.

Accession #

GenBank: BAD92448.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:50

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:50

Immunofluorescence

1:50

Immunohistochemistry

1:50

Western Blot

1:500

Protein

Uniprot #

P31483

Overview

Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Molecular Function

AU-rich element binding, nucleotide binding, poly(A) binding, poly (A) RNA binding

Subcellular Location

Cytoplasmic granule, nucleus. (Note: accumulates in cytoplasmic stress granules following cellular damage

Alternative Nomenclature

Cytotoxic granule associated RNA binding protein 1 antibody

Nucleolysin TIA 1 isoform p40 antibody

p40 TIA 1 antibody

p40-TIA-1 (containing p15-TIA-1) antibody

RNA binding protein TIA 1 antibody

T-cell-restricted intracellular antigen-1 antibody

TIA 1 cytotoxic granule associated RNA binding protein antibody

TIA1 cytotoxic granule associated RNA binding protein like 1 antibody

TIA1 protein antibody

TIAL1 antibody

TIAR antibody

General Information

Product

TIA1 Antibody

Description

Affinity Purified Nucleolysin TIA-1 isoform p40 Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 414-464 on human TIA1 protein.

Accession #

GenBank: BAD92448.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:50

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:50

Immunofluorescence

1:50

Immunohistochemistry

1:50

Western Blot

1:500

Protein

Uniprot #

P31483

Overview

Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

Molecular Function

AU-rich element binding, nucleotide binding, poly(A) binding, poly (A) RNA binding

Subcellular Location

Cytoplasmic granule, nucleus. (Note: accumulates in cytoplasmic stress granules following cellular damage

Alternative Nomenclature

Cytotoxic granule associated RNA binding protein 1 antibody

Nucleolysin TIA 1 isoform p40 antibody

p40 TIA 1 antibody

p40-TIA-1 (containing p15-TIA-1) antibody

RNA binding protein TIA 1 antibody

T-cell-restricted intracellular antigen-1 antibody

TIA 1 cytotoxic granule associated RNA binding protein antibody

TIA1 cytotoxic granule associated RNA binding protein like 1 antibody

TIA1 protein antibody

TIAL1 antibody

TIAR antibody

General Information

Product

CD45 Antibody

Description

Affinity Purified Receptor-type tyrosine-protein phosphatase C Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 1100-1150 on human Receptor-type tyrosine-protein phosphatase C.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500-1:5,000

Protein

Uniprot #

P08575

Subcellular Location

Cell membrane, Membrane

Structure

Repeat, Signal, Transmembrane, Transmembrane helix

Alternative Nomenclature

B220 antibody
CD45 antigen antibody
CD45R antibody
GP180 antibody
LCA antibody
Leukocyte common antigen antibody
loc antibody
Ly-5 antibody
LY5 antibody
Lyt-4 antibody
Protein tyrosine phosphatase receptor type c polypeptide antibody
Ptprc antibody
Receptor-type tyrosine-protein phosphatase C antibody
T200 antibody
T200 glycoprotein antibody
T200 leukocyte common antigen antibody